Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition

Natural hematopoietic stem cells (HSC) are susceptible and tend to lose stemness, differentiate, or die on culture condition in vitro, which adds technical challenge for maintaining bona fide HSC-like cells, if ever generated, in protocol screening from pluripotent stem cells. It remains largely unk...

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Publicado en:Cells
Autores principales: Dong, Yong, Xia, Chengxiang, Weng, Qitong, Wang, Tongjie, Hu, Fangxiao, Wang, Kaitao, Liu, Xiaofei, Geng, Yang, Liu, Lijuan, Wu, Hongling, Du, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770072/
https://ncbi.nlm.nih.gov/pubmed/31443434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8090951
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