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Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition

Natural hematopoietic stem cells (HSC) are susceptible and tend to lose stemness, differentiate, or die on culture condition in vitro, which adds technical challenge for maintaining bona fide HSC-like cells, if ever generated, in protocol screening from pluripotent stem cells. It remains largely unk...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Dong, Yong, Xia, Chengxiang, Weng, Qitong, Wang, Tongjie, Hu, Fangxiao, Wang, Kaitao, Liu, Xiaofei, Geng, Yang, Liu, Lijuan, Wu, Hongling, Du, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770072/
https://ncbi.nlm.nih.gov/pubmed/31443434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8090951
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