A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

The standard dosing of the Pfizer/BioNTech BNT162b2 mRNA vaccine validated in clinical trials includes two doses administered three weeks apart. While the decision by some public health authorities to space the doses because of limiting supply has raised concerns about vaccine efficacy, data indicat...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Tauzin, Alexandra, Nayrac, Manon, Benlarbi, Mehdi, Gong, Shang Yu, Gasser, Romain, Beaudoin-Bussières, Guillaume, Brassard, Nathalie, Laumaea, Annemarie, Vézina, Dani, Prévost, Jérémie, Anand, Sai Priya, Bourassa, Catherine, Gendron-Lepage, Gabrielle, Medjahed, Halima, Goyette, Guillaume, Niessl, Julia, Tastet, Olivier, Gokool, Laurie, Morrisseau, Chantal, Arlotto, Pascale, Stamatatos, Leonidas, McGuire, Andrew T., Larochelle, Catherine, Uchil, Pradeep, Lu, Maolin, Mothes, Walther, Serres, Gaston De, Moreira, Sandrine, Roger, Michel, Richard, Jonathan, Martel-Laferrière, Valérie, Duerr, Ralf, Tremblay, Cécile, Kaufmann, Daniel E., Finzi, Andrés
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987016/
https://ncbi.nlm.nih.gov/pubmed/33758857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.18.435972
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