A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses

While the standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two doses administered 3 weeks apart, some public health authorities are spacing these doses, raising concerns about efficacy. However, data indicate that a single dose can be up to 90% effective starting 14 days post-ad...

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Pubblicato in:Cell Host Microbe
Autori principali: Tauzin, Alexandra, Nayrac, Manon, Benlarbi, Mehdi, Gong, Shang Yu, Gasser, Romain, Beaudoin-Bussières, Guillaume, Brassard, Nathalie, Laumaea, Annemarie, Vézina, Dani, Prévost, Jérémie, Anand, Sai Priya, Bourassa, Catherine, Gendron-Lepage, Gabrielle, Medjahed, Halima, Goyette, Guillaume, Niessl, Julia, Tastet, Olivier, Gokool, Laurie, Morrisseau, Chantal, Arlotto, Pascale, Stamatatos, Leonidas, McGuire, Andrew T., Larochelle, Catherine, Uchil, Pradeep, Lu, Maolin, Mothes, Walther, De Serres, Gaston, Moreira, Sandrine, Roger, Michel, Richard, Jonathan, Martel-Laferrière, Valérie, Duerr, Ralf, Tremblay, Cécile, Kaufmann, Daniel E., Finzi, Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Inc. 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175625/
https://ncbi.nlm.nih.gov/pubmed/34133950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2021.06.001
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