DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing

The rapid global spread and continued evolution of SARS-CoV-2 has highlighted an unprecedented need for viral genomic surveillance and clinical viral sequencing. Amplicon-based sequencing methods provide a sensitive, low-cost and rapid approach but suffer a high potential for contamination, which ca...

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Pubblicato in:bioRxiv
Autori principali: Lagerborg, Kim A., Normandin, Erica, Bauer, Matthew R., Adams, Gordon, Figueroa, Katherine, Loreth, Christine, Gladden-Young, Adrianne, Shaw, Bennett, Pearlman, Leah, Shenoy, Erica S., Hooper, David, Pierce, Virginia M., Zachary, Kimon C., Park, Daniel J., MacInnis, Bronwyn L., Lemieux, Jacob E., Sabeti, Pardis C., Reilly, Steven K, Siddle, Katherine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987014/
https://ncbi.nlm.nih.gov/pubmed/33758855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.16.435654
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