Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes

There is an urgent need to develop effective interventions resistant to the evolving variants of SARS-CoV-2. Nanobodies (Nbs) are stable and cost-effective agents that can be delivered by novel aerosolization route to treat SARS-CoV-2 infections efficiently. However, it remains unknown if they posse...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Sun, Dapeng, Sang, Zhe, Kim, Yong Joon, Xiang, Yufei, Cohen, Tomer, Belford, Anna K., Huet, Alexis, Conway, James F., Sun, Ji, Taylor, Derek J., Schneidman-Duhovny, Dina, Zhang, Cheng, Huang, Wei, Shi, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987009/
https://ncbi.nlm.nih.gov/pubmed/33758850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.09.434592
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