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Integrative proteomics identifies thousands of distinct, multi-epitope, and high-affinity nanobodies

The antibody immune response is essential for the survival of mammals. However, we still lack a systematic understanding of the antibody repertoire. Here we developed a proteomic strategy to survey, at an unprecedented scale, the landscape of antigen-engaged, circulating camelid heavy-chain antibodi...

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Dettagli Bibliografici
Pubblicato in:Cell Syst
Autori principali: Xiang, Yufei, Sang, Zhe, Bitton, Lirane, Xu, Jianquan, Liu, Yang, Schneidman-Duhovny, Dina, Shi, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979497/
https://ncbi.nlm.nih.gov/pubmed/33592195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2021.01.003
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