Versatile, Multivalent Nanobody Cocktails Efficiently Neutralize SARS-CoV-2

The outbreak of COVID-19 has severely impacted global health and the economy. Cost-effective, highly efficacious therapeutics are urgently needed. Here, we used camelid immunization and proteomics to identify a large repertoire of highly potent neutralizing nanobodies (Nbs) to the SARS-CoV-2 spike (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:bioRxiv
Prif Awduron: Xiang, Yufei, Nambulli, Sham, Xiao, Zhengyun, Liu, Heng, Sang, Zhe, Duprex, W. Paul, Schneidman-Duhovny, Dina, Zhang, Cheng, Shi, Yi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457627/
https://ncbi.nlm.nih.gov/pubmed/32869034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.24.264333
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