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Synthetic nanobody–SARS-CoV-2 receptor-binding domain structures identify distinct epitopes

The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) demands unprecedented attention. We report four X-ray crystal structures of three synthetic nanobodies (sybodies) (Sb16, Sb45 and Sb68) bind to the receptor-binding domain (RBD) of SARS-CoV-2: binary complexes of Sb...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Ahmad, Javeed, Jiang, Jiansheng, Boyd, Lisa F., Natarajan, Kannan, Margulies, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852268/
https://ncbi.nlm.nih.gov/pubmed/33532775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.27.428466
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