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Functions for Retinoic Acid-Related Orphan Receptor Alpha (RORα) in the Activation of Macrophages During Lipopolysaccharide-Induced Septic Shock

The transcription factor Related Orphan Receptor Alpha (RORα) plays an important role in regulating circadian rhythm, inflammation, metabolism and cellular development. Herein we show that in the absence of functional RORα in mice there is reduced susceptibility to LPS-induced endotoxic shock, with...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Hams, Emily, Roberts, Joseph, Bermingham, Rachel, Fallon, Padraic G.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986717/
https://ncbi.nlm.nih.gov/pubmed/33767712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.647329
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