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Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity

The transcription factor RORα plays an important role in regulating circadian rhythm, inflammation, metabolism, and cellular development. Herein we show a role for RORα-expressing macrophages in the adipose tissue in altering the metabolic state of mice on a high-fat diet. The expression of Rora and...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hams, Emily, Roberts, Joseph, Bermingham, Rachel, Hogan, Andrew E., O'Shea, Donal, O'Neill, Luke, Fallon, Padraic G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482427/
https://ncbi.nlm.nih.gov/pubmed/32973801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01966
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