Btk Regulates Macrophage Polarization in Response to Lipopolysaccharide

Bacterial Lipopolysaccharide (LPS) is a strong inducer of inflammation and does so by inducing polarization of macrophages to the classic inflammatory M1 population. Given the role of Btk as a critical signal transducer downstream of TLR4, we investigated its role in M1/M2 induction. In Btk deficien...

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Detalhes bibliográficos
Main Authors: Ní Gabhann, Joan, Hams, Emily, Smith, Siobhán, Wynne, Claire, Byrne, Jennifer C., Brennan, Kiva, Spence, Shaun, Kissenpfennig, Adrien, Johnston, James A., Fallon, Padraic G., Jefferies, Caroline A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897530/
https://ncbi.nlm.nih.gov/pubmed/24465735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085834
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