Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production

Although production of cytokines by TLR is essential for viral and bacterial clearance, overproduction can be detrimental, thus controlling these responses is essential. CD33-related sialic acid binding Ig-like lectin receptors (Siglecs) have been implicated in the control of leukocyte responses. In...

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Publicado no:J Immunol
Main Authors: Boyd, Caroline R., Orr, Selinda J., Spence, Shaun, Burrows, James F., Elliott, Joanne, Carroll, Helen P., Brennan, Kiva, Ní Gabhann, Joan, Coulter, Wilson A., Johnston, James A., Jefferies, Caroline A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580793/
https://ncbi.nlm.nih.gov/pubmed/19933851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902780
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