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Base‐Free Pd‐Catalyzed C−Cl Borylation of Fluorinated Aryl Chlorides

Catalytic C−X borylation of aryl halides containing two ortho‐fluorines has been found to be challenging, as most previous methods require stoichiometric amounts of base and the polyfluorinated aryl boronates suffer from protodeboronation, which is accelerated by ortho‐fluorine substituents. Herein,...

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Publicado en:Chemistry
Main Authors: Budiman, Yudha P., Lorenzen, Sabine, Liu, Zhiqiang, Radius, Udo, Marder, Todd B.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986610/
https://ncbi.nlm.nih.gov/pubmed/33197081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004648
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