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Base‐Free Pd‐Catalyzed C−Cl Borylation of Fluorinated Aryl Chlorides

Catalytic C−X borylation of aryl halides containing two ortho‐fluorines has been found to be challenging, as most previous methods require stoichiometric amounts of base and the polyfluorinated aryl boronates suffer from protodeboronation, which is accelerated by ortho‐fluorine substituents. Herein,...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Budiman, Yudha P., Lorenzen, Sabine, Liu, Zhiqiang, Radius, Udo, Marder, Todd B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986610/
https://ncbi.nlm.nih.gov/pubmed/33197081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004648
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