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4‐1BB costimulation promotes bystander activation of human CD8 T cells

Costimulatory signals potently promote T‐cell proliferation and effector function. Agonistic antibodies targeting costimulatory receptors of the TNFR family, such as 4‐1BB and CD27, have entered clinical trials in cancer patients. Currently there is limited information how costimulatory signals regu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Immunol
Prif Awduron: Reithofer, Manuel, Rosskopf, Sandra, Leitner, Judith, Battin, Claire, Bohle, Barbara, Steinberger, Peter, Jahn‐Schmid, Beatrice
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986150/
https://ncbi.nlm.nih.gov/pubmed/33180337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048762
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