4‐1BB costimulation promotes bystander activation of human CD8 T cells

Costimulatory signals potently promote T‐cell proliferation and effector function. Agonistic antibodies targeting costimulatory receptors of the TNFR family, such as 4‐1BB and CD27, have entered clinical trials in cancer patients. Currently there is limited information how costimulatory signals regu...

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Bibliografiska uppgifter
I publikationen:Eur J Immunol
Huvudupphovsmän: Reithofer, Manuel, Rosskopf, Sandra, Leitner, Judith, Battin, Claire, Bohle, Barbara, Steinberger, Peter, Jahn‐Schmid, Beatrice
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2020
Ämnen:
Immunomodulation and immune therapies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986150/
https://ncbi.nlm.nih.gov/pubmed/33180337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048762
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