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4‐1BB costimulation promotes bystander activation of human CD8 T cells

Costimulatory signals potently promote T‐cell proliferation and effector function. Agonistic antibodies targeting costimulatory receptors of the TNFR family, such as 4‐1BB and CD27, have entered clinical trials in cancer patients. Currently there is limited information how costimulatory signals regu...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Reithofer, Manuel, Rosskopf, Sandra, Leitner, Judith, Battin, Claire, Bohle, Barbara, Steinberger, Peter, Jahn‐Schmid, Beatrice
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986150/
https://ncbi.nlm.nih.gov/pubmed/33180337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048762
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