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Response adaptive designs for Phase II trials with binary endpoint based on context-dependent information measures()

In many rare disease Phase II clinical trials, two objectives are of interest to an investigator: maximising the statistical power and maximising the number of patients responding to the treatment. These two objectives are competing, therefore, clinical trial designs offering a balance between them...

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Detalhes bibliográficos
Publicado no:Comput Stat Data Anal
Main Authors: Kasianova, Ksenia, Kelbert, Mark, Mozgunov, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985674/
https://ncbi.nlm.nih.gov/pubmed/34083846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2021.107187
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