Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility Along with Blood Pressure

Short-chain fatty acids (SCFAs) are metabolites produced almost exclusively by the gut microbiota and are an essential mechanism by which gut microbes influence host physiology. Given that SCFAs induce vasodilation, we hypothesized that they might have additional cardiovascular effects. In this stud...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Poll, Brian G., Xu, Jiaojiao, Jun, Seungho, Sanchez, Jason, Zaidman, Nathan A., He, Xiaojun, Lester, Laeben, Berkowitz, Dan E., Paolocci, Nazareno, Gao, Wei Dong, Pluznick, Jennifer L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2021
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985618/
https://ncbi.nlm.nih.gov/pubmed/33414131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000187
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