Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility Along with Blood Pressure

Short-chain fatty acids (SCFAs) are metabolites produced almost exclusively by the gut microbiota and are an essential mechanism by which gut microbes influence host physiology. Given that SCFAs induce vasodilation, we hypothesized that they might have additional cardiovascular effects. In this stud...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Poll, Brian G., Xu, Jiaojiao, Jun, Seungho, Sanchez, Jason, Zaidman, Nathan A., He, Xiaojun, Lester, Laeben, Berkowitz, Dan E., Paolocci, Nazareno, Gao, Wei Dong, Pluznick, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2021
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985618/
https://ncbi.nlm.nih.gov/pubmed/33414131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000187
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