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A Potential Role for SerpinA3N in Acetaminophen-Induced Hepatotoxicity

Acetaminophen (APAP) is a commonly used pain and fever reliever but is also the most frequent cause of drug-induced liver injury. The mechanism pertaining acetaminophen toxicity has been well documented, whereas mechanisms of hepatotoxicity are not well established. Serine (or cysteine) peptidase in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Pharmacol
Main Authors: Tran, Melanie, Wu, Jianguo, Wang, Li, Shin, Dong-Ju
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985612/
https://ncbi.nlm.nih.gov/pubmed/33436521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000117
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