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The clinical applicability of polygenic risk scores for LDL-cholesterol: considerations, current evidence and future perspectives
The current review describes the development, clinical relevance and potential caveats of polygenic risk scores (PRS) for LDL cholesterol (LDL-C). RECENT FINDINGS: In recent years, a large number of common variants have been shown to have a small effect on LDL-C levels. The aggregate effect of all o...
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| Publicat a: | Curr Opin Lipidol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Lippincott Williams & Wilkins
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7984749/ https://ncbi.nlm.nih.gov/pubmed/33560669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0000000000000741 |
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