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The need for polygenic score reporting standards in evidence-based practice: lipid genetics use case

Polygenic scores (PGS) are used to quantify the genetic predisposition for heritable traits, with hypothesized utility for personalized risk assessments. Lipid PGS are primed for clinical translation, but evidence-based practice changes will require rigorous PGS standards to ensure reproducibility a...

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Bibliografiske detaljer
Udgivet i:Curr Opin Lipidol
Main Authors: Wand, Hannah, Knowles, Joshua W., Clarke, Shoa L.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962796/
https://ncbi.nlm.nih.gov/pubmed/33538426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOL.0000000000000733
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