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Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration

Cell migration in 3D microenvironments is a complex process which depends on the coordinated activity of leading edge protrusive force and rear retraction in a push-pull mechanism. While the potentiation of protrusions has been widely studied, the precise signalling and mechanical events that lead t...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Hetmanski, Joseph H. R., Jones, Matthew C., Chunara, Fatima, Schwartz, Jean-Marc, Caswell, Patrick T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984637/
https://ncbi.nlm.nih.gov/pubmed/33690598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008213
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