Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration

In development, wound healing, and cancer metastasis, vertebrate cells move through 3D interstitial matrix, responding to chemical and physical guidance cues. Protrusion at the cell front has been extensively studied, but the retraction phase of the migration cycle is not well understood. Here, we s...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Hetmanski, Joseph H.R., de Belly, Henry, Busnelli, Ignacio, Waring, Thomas, Nair, Roshna V., Sokleva, Vanesa, Dobre, Oana, Cameron, Angus, Gauthier, Nils, Lamaze, Christophe, Swift, Joe, del Campo, Aránzazu, Starborg, Tobias, Zech, Tobias, Goetz, Jacky G., Paluch, Ewa K., Schwartz, Jean-Marc, Caswell, Patrick T.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863396/
https://ncbi.nlm.nih.gov/pubmed/31607653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.09.006
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