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TRPM3 Channels Play Roles in Heat Hypersensitivity and Spontaneous Pain after Nerve Injury

Transient receptor potential melastatin 3 (TRPM3) is a heat-activated ion channel in primary sensory neurons of the dorsal root ganglia (DRGs). Pharmacological and genetic studies implicated TRPM3 in various pain modalities, but TRPM3 inhibitors were not validated in TRPM3(−/−) mice. Here we tested...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Su, Songxue, Yudin, Yevgen, Kim, Nawoo, Tao, Yuan-Xiang, Rohacs, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984590/
https://ncbi.nlm.nih.gov/pubmed/33478988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1551-20.2020
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