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Clusterin regulates macrophage expansion, polarization and phagocytic activity in response to inflammation in the kidneys

Clusterin (CLU) is a multifunctional protein localized extracellularly and intracellularly. Although CLU‐knockout (KO) mice are more susceptible to renal ischemia‐reperfusion injury (IRI), the mechanisms underlying the actions of CLU in IRI are not fully understood. Macrophages are key regulators of...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Weng, Xiaodong, Zhao, Haimei, Guan, Qiunong, Shi, Ganggang, Feng, Shijian, Gleave, Martin E, Nguan, Christopher CY, Du, Caigan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984284/
https://ncbi.nlm.nih.gov/pubmed/32935392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12405
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