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Clusterin regulates macrophage expansion, polarization and phagocytic activity in response to inflammation in the kidneys

Clusterin (CLU) is a multifunctional protein localized extracellularly and intracellularly. Although CLU‐knockout (KO) mice are more susceptible to renal ischemia‐reperfusion injury (IRI), the mechanisms underlying the actions of CLU in IRI are not fully understood. Macrophages are key regulators of...

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Publicat a:Immunol Cell Biol
Autors principals: Weng, Xiaodong, Zhao, Haimei, Guan, Qiunong, Shi, Ganggang, Feng, Shijian, Gleave, Martin E, Nguan, Christopher CY, Du, Caigan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984284/
https://ncbi.nlm.nih.gov/pubmed/32935392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12405
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