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Clusterin regulates macrophage expansion, polarization and phagocytic activity in response to inflammation in the kidneys

Clusterin (CLU) is a multifunctional protein localized extracellularly and intracellularly. Although CLU‐knockout (KO) mice are more susceptible to renal ischemia‐reperfusion injury (IRI), the mechanisms underlying the actions of CLU in IRI are not fully understood. Macrophages are key regulators of...

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Dettagli Bibliografici
Pubblicato in:Immunol Cell Biol
Autori principali: Weng, Xiaodong, Zhao, Haimei, Guan, Qiunong, Shi, Ganggang, Feng, Shijian, Gleave, Martin E, Nguan, Christopher CY, Du, Caigan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984284/
https://ncbi.nlm.nih.gov/pubmed/32935392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12405
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