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Halofuginone Synergistically Enhances Anti-Proliferation of Rapamycin in T Cells and Reduces Cytotoxicity of Cyclosporine in Cultured Renal Tubular Epithelial Cells

Both rapamycin (RAPA) and cyclosporin A (CsA) are commonly used for immunosuppression, however their adverse side effects limit their application. Thus, it is of interest to develop novel means to enhance or preserve the immunosuppressive activity of RAPA or CsA while reducing their toxicity. Halofu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chu, Tony L. H., Guan, Qiunong, Nguan, Christopher Y. C., Du, Caigan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686009/
https://ncbi.nlm.nih.gov/pubmed/26671563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144735
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