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The biogenesis and biology of amyloid β oligomers in the brain

The repeated failure of clinical trials targeting the amyloid beta (Aβ) protein has challenged the amyloid cascade hypothesis. In this perspective, I discuss the biogenesis and biology of Aβ, from the arrangement of its atoms to its effects on the human brain. I hope that this analysis will help gui...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Autor principal: Ashe, Karen Hsiao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984270/
https://ncbi.nlm.nih.gov/pubmed/32543725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12084
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