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Drug‐drug interaction of atazanavir on UGT1A1‐mediated glucuronidation of molidustat in human
Molidustat is an oral inhibitor of hypoxia‐inducible factor (HIF) prolyl‐hydroxylase enhancing the erythropoietin (EPO) response to HIF; it is in clinical development for the treatment of anaemia related to chronic kidney disease. The predominant role of glucuronidation for molidustat clearance (for...
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| Publicado no: | Basic Clin Pharmacol Toxicol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7983974/ https://ncbi.nlm.nih.gov/pubmed/33232579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.13538 |
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