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ADP-Ribosylation Regulates the Signaling Function of IFN-γ
Murine T cells express the GPI-anchored ADP-ribosyltransferase 2.2 (ARTC2.2) on the cell surface. In response to T cell activation or extracellular NAD(+) or ATP-mediated gating of the P2X7 ion channel ARTC2.2 is shed from the cell surface as a soluble enzyme. Shedding alters the target specificity...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7983947/ https://ncbi.nlm.nih.gov/pubmed/33763084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.642545 |
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