Tolerance to Opioid‐Induced Respiratory Depression in Chronic High‐Dose Opioid Users: A Model‐Based Comparison With Opioid‐Naïve Individuals

Chronic opioid consumption is associated with addiction, physical dependence, and tolerance. Tolerance results in dose escalation to maintain the desired opioid effect. Intake of high‐dose or potent opioids may cause life‐threatening respiratory depression, an effect that may be reduced by tolerance...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Algera, Marijke Hyke, Olofsen, Erik, Moss, Laurence, Dobbins, Robert L., Niesters, Marieke, van Velzen, Monique, Groeneveld, Geert Jan, Heuberger, Jules, Laffont, Celine M., Dahan, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983936/
https://ncbi.nlm.nih.gov/pubmed/32865832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.2027
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky