Opioid-induced respiratory depression: reversal by non-opioid drugs

The human body is critically dependent on the ventilatory control system for adequate uptake of oxygen and removal of carbon dioxide (CO(2)). Potent opioid analgesics, through their actions on μ-opioid receptor (MOR) expressed on respiratory neurons in the brainstem, depress ventilation. Opioid-indu...

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Bibliographic Details
Main Authors: van der Schier, Rutger, Roozekrans, Margot, van Velzen, Monique, Dahan, Albert, Niesters, Marieke
Format: Artigo
Language:Inglês
Published: Faculty of 1000 Ltd 2014
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173639/
https://ncbi.nlm.nih.gov/pubmed/25343036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P6-79
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