Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres

There is an unmet need for novel biomarkers in the diagnosis of multifactorial COPD. We applied next-generation proteomics to serum extracellular vesicles (EVs) to discover novel COPD biomarkers. EVs from 10 patients with COPD and six healthy controls were analysed by tandem mass tag-based non-targe...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: Koba, Taro, Takeda, Yoshito, Narumi, Ryohei, Shiromizu, Takashi, Nojima, Yosui, Ito, Mari, Kuroyama, Muneyoshi, Futami, Yu, Takimoto, Takayuki, Matsuki, Takanori, Edahiro, Ryuya, Nojima, Satoshi, Hayama, Yoshitomo, Fukushima, Kiyoharu, Hirata, Haruhiko, Koyama, Shohei, Iwahori, Kota, Nagatomo, Izumi, Suzuki, Mayumi, Shirai, Yuya, Murakami, Teruaki, Nakanishi, Kaori, Nakatani, Takeshi, Suga, Yasuhiko, Miyake, Kotaro, Shiroyama, Takayuki, Kida, Hiroshi, Sasaki, Takako, Ueda, Koji, Mizuguchi, Kenji, Adachi, Jun, Tomonaga, Takeshi, Kumanogoh, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2021
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983195/
https://ncbi.nlm.nih.gov/pubmed/33778046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00658-2020
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