Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing’s sarcoma cells

INTRODUCTION: Ewing's sarcoma is an aggressive childhood malignancy whose outcome has not substantially improved over the last two decades. In this study, combination treatments of the HSP90 inhibitor AUY922 with either the ATR inhibitor VE821 or the ATM inhibitor KU55933 were investigated for...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Marx, Christian, Schaarschmidt, Marc U., Kirkpatrick, Joanna, Marx-Blümel, Lisa, Halilovic, Melisa, Westermann, Martin, Hoelzer, Doerte, Meyer, Felix B., Geng, Yibo, Buder, Katrin, Schadwinkel, Hauke M., Siniuk, Kanstantsin, Becker, Sabine, Thierbach, René, Beck, James F., Sonnemann, Jürgen, Wang, Zhao-Qi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981928/
https://ncbi.nlm.nih.gov/pubmed/33743824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00571-y
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