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SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints

BACKGROUND: Combined whole-genome sequencing (WGS) and RNA sequencing of cancers offer the opportunity to identify genes with altered expression due to genomic rearrangements. Somatic structural variants (SVs), as identified by WGS, can involve altered gene cis-regulation, gene fusions, copy number...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Zhang, Yiqun, Chen, Fengju, Creighton, Chad J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981925/
https://ncbi.nlm.nih.gov/pubmed/33743584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04072-0
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