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Systematic identification of non-coding somatic single nucleotide variants associated with altered transcription and DNA methylation in adult and pediatric cancers

Whole-genome sequencing combined with transcriptomics can reveal impactful non-coding single nucleotide variants (SNVs) in cancer. Here, we developed an integrative analytical approach that, as a first step, identifies genes altered in expression or DNA methylation in association with nearby somatic...

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Detalhes bibliográficos
Publicado no:NAR Cancer
Main Authors: Chen, Fengju, Zhang, Yiqun, Creighton, Chad J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849833/
https://ncbi.nlm.nih.gov/pubmed/33554123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcab001
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