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SVExpress: identifying gene features altered recurrently in expression with nearby structural variant breakpoints

BACKGROUND: Combined whole-genome sequencing (WGS) and RNA sequencing of cancers offer the opportunity to identify genes with altered expression due to genomic rearrangements. Somatic structural variants (SVs), as identified by WGS, can involve altered gene cis-regulation, gene fusions, copy number...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Zhang, Yiqun, Chen, Fengju, Creighton, Chad J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981925/
https://ncbi.nlm.nih.gov/pubmed/33743584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04072-0
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