ERAPs Reduce In Vitro HIV Infection by Activating Innate Immune Response

Recombinant human (rh) ERAP2-treated PBMCs are less susceptible to in vitro HIV-1 infection even when CD8(+) T cells are depleted. We therefore investigated whether ERAP2 can trigger other immunocompetent cells, boosting their antiviral potential. To this end, human monocyte-derived macrophages (MDM...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Saulle, Irma, Marventano, Ivana, Saresella, Marina, Vanetti, Claudia, Garziano, Micaela, Fenizia, Claudio, Trabattoni, Daria, Clerici, Mario, Biasin, Mara
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2021
Fag:
Innate Immunity and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980528/
https://ncbi.nlm.nih.gov/pubmed/33619214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000991
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