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An Overview on ERAP Roles in Infectious Diseases
Endoplasmic reticulum (ER) aminopeptidases ERAP1 and ERAP2 (ERAPs) are crucial enzymes shaping the major histocompatibility complex I (MHC I) immunopeptidome. In the ER, these enzymes cooperate in trimming the N-terminal residues from precursors peptides, so as to generate optimal-length antigens to...
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| Udgivet i: | Cells |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7140696/ https://ncbi.nlm.nih.gov/pubmed/32183384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030720 |
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