Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection

Background: Haplotype-specific alternative splicing of the endoplasmic reticulum (ER) aminopeptidase type 2 (ERAP2) gene results in either full-length (FL, haplotype A) or alternatively spliced (AS, haplotype B) mRNA. HapA/HapA homozygous (HomoA) subjects show a reduced susceptibility to HIV-1 infec...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Saulle, Irma, Ibba, Salomè Valentina, Torretta, Enrica, Vittori, Cecilia, Fenizia, Claudio, Piancone, Federica, Minisci, Davide, Lori, Elisa Maria, Trabattoni, Daria, Gelfi, Cecilia, Clerici, Mario, Biasin, Mara
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646713/
https://ncbi.nlm.nih.gov/pubmed/31379846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01648
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