Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment

Malignant Pleural Mesothelioma (MPM) is typically diagnosed 20–50 years after exposure to asbestos and evolves along an unknown evolutionary trajectory. To elucidate this path, we conducted multi-regional exome sequencing of 90 tumour samples from 22 MPMs acquired at surgery. Here we show that exomi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Zhang, Min, Luo, Jin-Li, Sun, Qianqian, Harber, James, Dawson, Alan G., Nakas, Apostolos, Busacca, Sara, Sharkey, Annabel J., Waller, David, Sheaff, Michael T., Richards, Cathy, Wells-Jordan, Peter, Gaba, Aarti, Poile, Charlotte, Baitei, Essa Y., Bzura, Aleksandra, Dzialo, Joanna, Jama, Maymun, Le Quesne, John, Bajaj, Amrita, Martinson, Luke, Shaw, Jacqui A., Pritchard, Catrin, Kamata, Tamihiro, Kuse, Nathaniel, Brannan, Lee, De Philip Zhang, Pan, Yang, Hongji, Griffiths, Gareth, Wilson, Gareth, Swanton, Charles, Dudbridge, Frank, Hollox, Edward J., Fennell, Dean A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979861/
https://ncbi.nlm.nih.gov/pubmed/33741915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21798-w
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars