A platform for experimental precision medicine: The extended BXD mouse family

The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to 140 fully isogenic strains, creating a uniquely powerful model for precision medicine. This...

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Dades bibliogràfiques
Publicat a:Cell Syst
Autors principals: Ashbrook, David G., Arends, Danny, Prins, Pjotr, Mulligan, Megan K., Roy, Suheeta, Williams, Evan G., Lutz, Cathleen M., Valenzuela, Alicia, Bohl, Casey J., Ingels, Jesse F., McCarty, Melinda S., Centeno, Arthur G., Hager, Reinmar, Auwerx, Johan, Lu, Lu, Williams, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979527/
https://ncbi.nlm.nih.gov/pubmed/33472028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.12.002
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