A platform for experimental precision medicine: The extended BXD mouse family

The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to 140 fully isogenic strains, creating a uniquely powerful model for precision medicine. This...

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Publicado en:Cell Syst
Main Authors: Ashbrook, David G., Arends, Danny, Prins, Pjotr, Mulligan, Megan K., Roy, Suheeta, Williams, Evan G., Lutz, Cathleen M., Valenzuela, Alicia, Bohl, Casey J., Ingels, Jesse F., McCarty, Melinda S., Centeno, Arthur G., Hager, Reinmar, Auwerx, Johan, Lu, Lu, Williams, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979527/
https://ncbi.nlm.nih.gov/pubmed/33472028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.12.002
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