A platform for experimental precision medicine: The extended BXD mouse family

The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to 140 fully isogenic strains, creating a uniquely powerful model for precision medicine. This...

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Vydáno v:Cell Syst
Hlavní autoři: Ashbrook, David G., Arends, Danny, Prins, Pjotr, Mulligan, Megan K., Roy, Suheeta, Williams, Evan G., Lutz, Cathleen M., Valenzuela, Alicia, Bohl, Casey J., Ingels, Jesse F., McCarty, Melinda S., Centeno, Arthur G., Hager, Reinmar, Auwerx, Johan, Lu, Lu, Williams, Robert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979527/
https://ncbi.nlm.nih.gov/pubmed/33472028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.12.002
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