A platform for experimental precision medicine: The extended BXD mouse family

The challenge of precision medicine is to model complex interactions among DNA variants, phenotypes, development, environments, and treatments. We address this challenge by expanding the BXD family of mice to 140 fully isogenic strains, creating a uniquely powerful model for precision medicine. This...

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Библиографические подробности
Опубликовано в: :Cell Syst
Главные авторы: Ashbrook, David G., Arends, Danny, Prins, Pjotr, Mulligan, Megan K., Roy, Suheeta, Williams, Evan G., Lutz, Cathleen M., Valenzuela, Alicia, Bohl, Casey J., Ingels, Jesse F., McCarty, Melinda S., Centeno, Arthur G., Hager, Reinmar, Auwerx, Johan, Lu, Lu, Williams, Robert W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979527/
https://ncbi.nlm.nih.gov/pubmed/33472028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.12.002
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