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Regulation of post-ischemic inflammatory response: A novel function of the neuronal tyrosine phosphatase STEP

The neuron-specific tyrosine phosphatase STEP is emerging as a key neuroprotectant against acute ischemic stroke. However, it remains unclear how STEP impacts the outcome of stroke. We find that the exacerbation of ischemic brain injury in STEP deficient mice involves an early onset and sustained ac...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Rajagopal, Sathyanarayanan, Yang, Changjun, DeMars, Kelly M., Poddar, Ranjana, Candelario-Jalil, Eduardo, Paul, Surojit
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979508/
https://ncbi.nlm.nih.gov/pubmed/33422638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.12.034
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