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Aging is associated with dimerization and inactivation of the brain-enriched tyrosine phosphatase STEP

The striatal-enriched tyrosine phosphatase (STEP) is involved in the etiology of several age-associated neurological disorders linked to oxidative stress and is also known to play a role in neuroprotection by modulating glutamatergic transmission. However, the possible effect of aging on STEP level...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Rajagopal, Sathyanarayanan, Deb, Ishani, Poddar, Ranjana, Paul, Surojit
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841919/
https://ncbi.nlm.nih.gov/pubmed/27103516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.02.004
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