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Role of type I interferons and innate immunity in systemic sclerosis: unbalanced activities on distinct cell types?

PURPOSE OF REVIEW: The role of type I IFNs (IFN-I) in the promotion of autoimmunity has been well established. However, its role in the skin fibrosis of systemic sclerosis (SSc) is less clear. IFN-I can participate to tissue repair, and, here, we will consider the extent to which IFN-I’s role in SSc...

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Vydáno v:Curr Opin Rheumatol
Hlavní autoři: Barrat, Franck J., Lu, Theresa T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977624/
https://ncbi.nlm.nih.gov/pubmed/31436583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0000000000000659
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