Evasion of the Innate Immune Type I Interferon System by Monkeypox Virus

The vaccinia virus (VACV) E3 protein has been shown to be important for blocking activation of the cellular innate immune system and allowing viral replication to occur unhindered. Mutation or deletion of E3L severely affects viral host range and pathogenesis. While the monkeypox virus (MPXV) genome...

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Vydáno v:J Virol
Hlavní autoři: Arndt, William D., Cotsmire, Samantha, Trainor, Kelly, Harrington, Heather, Hauns, Kevin, Kibler, Karen V., Huynh, Trung P., Jacobs, Bertram L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580173/
https://ncbi.nlm.nih.gov/pubmed/26246580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00304-15
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