Evasion of the Innate Immune Type I Interferon System by Monkeypox Virus

The vaccinia virus (VACV) E3 protein has been shown to be important for blocking activation of the cellular innate immune system and allowing viral replication to occur unhindered. Mutation or deletion of E3L severely affects viral host range and pathogenesis. While the monkeypox virus (MPXV) genome...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Arndt, William D., Cotsmire, Samantha, Trainor, Kelly, Harrington, Heather, Hauns, Kevin, Kibler, Karen V., Huynh, Trung P., Jacobs, Bertram L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580173/
https://ncbi.nlm.nih.gov/pubmed/26246580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00304-15
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