Evasion of the Innate Immune Type I Interferon System by Monkeypox Virus

The vaccinia virus (VACV) E3 protein has been shown to be important for blocking activation of the cellular innate immune system and allowing viral replication to occur unhindered. Mutation or deletion of E3L severely affects viral host range and pathogenesis. While the monkeypox virus (MPXV) genome...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Arndt, William D., Cotsmire, Samantha, Trainor, Kelly, Harrington, Heather, Hauns, Kevin, Kibler, Karen V., Huynh, Trung P., Jacobs, Bertram L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580173/
https://ncbi.nlm.nih.gov/pubmed/26246580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00304-15
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